Ingredient glossary
Neurological

Valerian Root

Valeriana officinalis

Also known as: Garden Valerian, All-Heal, Setwall

Overview

A widely studied European herb with strong clinical evidence for improving sleep quality, sleep latency, and anxiety reduction through multiple GABA-A receptor pathways.

Proposed mechanism

Valerenic acid binds to GABA-A receptor subtypes (β3) and inhibits GABA reuptake and degradation, increasing inhibitory neurotransmitter availability. Also reduces adenosine breakdown.

Mechanisms describe how researchers think a compound may act, often from laboratory work — a proposed mechanism is not proof of a clinical effect in people.

Traditional & studied uses

Sleep SupportMood Support

Related pathways

Chronic Stress Physiology

Pathway tags are a research aid for browsing the glossary — they are not a claim that this ingredient treats any condition.

Traditional medicine systems

Western Herbalism